Analysis of the computational model mechatronic system design and its dynamic behavior

Tato bakalářská práce se zabývá výpočtovým modelováním příčníku obráběcího stroje v programu Ansys Workbench. Cílem práce bylo určení dynamických vlastností této konstrukce, provedení statické analýzy a dále pak exportování modelu do prostředí MSC Adams.This bachelor thesis deals with the computational model of crosspiece of a machine tool in software Ansys Workbench. Aim of this thesis was to compute dynamic characteristics of this construction, perform structural analysis and export the model to MSC Adams environment.

Design of Door Frame Curvature

Tato diplomová práce se zabývá návrhem zakřivení rámu dveřního křídla určeného pro kolejové vozidlo. Na zakřivený rám se lepí rovné sklo, vlivem elastické deformace po nalepení skla dochází k ohnutí rámu na opačnou stranu. Samotný rám je tedy potřeba předehnout tak, aby vzniklá rezerva pokryla zpětný ohyb skla. Pomocí metody konečných prvků byla provedena analýza současně vyráběných dveří s konstantním poloměrem a ověřena vhodnost zvoleného přístupu k řešenému problému. Návrh zakřivení je poté proveden pro dveře s kombinovaným poloměrem zakřivení (rozdílným v dolní a horní části dveří). Cílem této práce bylo navrhnutí zakřivení dveřního rámu tak, aby po nalepení skla mělo dveřní křídlo požadovaný tvar.This diploma thesis deals with the design of door frame curvature, meant for rail vehicle. Flat glass is adhesively bonded onto the curved door frame and due to the elastic deformation the door frame bends backwards. Hence the door frame must be bend with reserve so that the elastic deformation is covered. Finite element analysis of currently manufactured door with constant curvatere has been carried out, with this analysis it has been checked that the chosen problem approach is suitable. Design of door frame curvature is then made for door frame with combined curvature (different for lower and upper part of door frame). The aim of this thesis was to design the curvature so that after glass is bonded onto it, the door frame will have the right dimensions.

Von der Geworfenheit zur Getragenheit

Die vorliegende Arbeit befasst sich mit der Transformation des Heideggerschen Seinsbegriffes durch die Philosophie Peter Sloterdijks. Dabei werden im ersten Teil als Grundlage für die weitere Erkundung die wichtigsten Positionen des Existenzialismus von Martin Heidegger genau analysiert. Der Fokus liegt hier vor allem auf Heideggers Frage nach dem Sein und deren Verlegung ins einzelne Dasein. Schließlich wird Heideggers Untersuchung des Alltags dieses Daseins einer Prüfung unterzogen. Das Hauptaugenmerk liegt dabei auf der Darstellung folgender von Heidegger so benannten Existenzialien: das In-der-Welt-Sein, die Verfallenheit an das Man, die Geworfenheit, die Angst, die Sorge, die Fürsorge, die Sorge im Umgang mit Dingen, das Sein zum Tode und dem Ruf der Eigentlichkeit. Die Ergebnisse dieser Darstellung werden dann mit dem Daseins-Verständnis von Peter Sloterdijk in Vergleich gesetzt. Im zweiten Teil der Arbeit wird zuerst eine Einordnung von Sloterdijks Werk ins Koordinatensystem der Philosophie vorgenommen. Danach folgt eine ausführliche Analyse seiner besonderen Schreibmethode. Unter dem Stichwort „Sphärologie“ wird die Existenzgeschichte des Menschen sowohl mikro- als auch makrohistorisch nachgezeichnet. Die aus der „Sphärologie“ gewonnenen Erkenntnisse werden Heideggers Existenzialien gegenübergestellt. Nun kann verständlich gemacht werden, wo die entscheidenden Kritikpunkte Sloterdijks an der Heideggerschen Existenzphilosophie zu finden sind und des Weiteren, wo und mit welchen Mitteln Sloterdijk an Heidegger anschließt, und einige seiner Thesen in die Sprache des 21. Jahrhunderts transformiert

Role of Sb in the superconducting kagome metal CsV$3Sb5 revealed by its anisotropic compression

Pressure evolution of the superconducting kagome metal CsV$_3$Sb$_5$ is studied with single-crystal x-ray diffraction and density-functional band-structure calculations. A highly anisotropic compression observed up to 5 GPa is ascribed to the fast shrinkage of the Cs-Sb distances and suppression of Cs rattling motion. This prevents Sb displacements required to stabilize the three-dimensional charge-density-wave (CDW) order and elucidates the disappearance of the CDW already at 2 GPa despite only minor changes in the electronic structure of the normal state. At higher pressures, vanadium bands still change only marginally, whereas antimony bands undergo a major reconstruction caused by the gradual formation of the interlayer Sb-Sb bonds. Our results exclude pressure tuning of vanadium kagome bands as the main mechanism for the non-trivial evolution of superconductivity in real-world kagome metals. Concurrently, we establish the central role of Sb atoms in the stabilization of a three-dimensional CDW and Fermi surface reconstruction.Comment: published versio

Predicting Gene Expression Level from Relative Codon Usage Bias: An Application to Escherichia coli Genome

We present an expression measure of a gene, devised to predict the level of gene expression from relative codon bias (RCB). There are a number of measures currently in use that quantify codon usage in genes. Based on the hypothesis that gene expressivity and codon composition is strongly correlated, RCB has been defined to provide an intuitively meaningful measure of an extent of the codon preference in a gene. We outline a simple approach to assess the strength of RCB (RCBS) in genes as a guide to their likely expression levels and illustrate this with an analysis of Escherichia coli (E. coli) genome. Our efforts to quantitatively predict gene expression levels in E. coli met with a high level of success. Surprisingly, we observe a strong correlation between RCBS and protein length indicating natural selection in favour of the shorter genes to be expressed at higher level. The agreement of our result with high protein abundances, microarray data and radioactive data demonstrates that the genomic expression profile available in our method can be applied in a meaningful way to the study of cell physiology and also for more detailed studies of particular genes of interest

Ultrafast Nanoscopy of High-Density Exciton Phases in WSe2

The density-driven transition of an exciton gas into an electron–hole plasma remains a compelling question in condensed matter physics. In two-dimensional transition metal dichalcogenides, strongly bound excitons can undergo this phase change after transient injection of electron–hole pairs. Unfortunately, unavoidable nanoscale inhomogeneity in these materials has impeded quantitative investigation into this elusive transition. Here, we demonstrate how ultrafast polarization nanoscopy can capture the Mott transition through the density-dependent recombination dynamics of electron–hole pairs within a WSe2 homobilayer. For increasing carrier density, an initial monomolecular recombination of optically dark excitons transitions continuously into a bimolecular recombination of an unbound electron–hole plasma above 7 × 1012 cm–2. We resolve how the Mott transition modulates over nanometer length scales, directly evidencing the strong inhomogeneity in stacked monolayers. Our results demonstrate how ultrafast polarization nanoscopy could unveil the interplay of strong electronic correlations and interlayer coupling within a diverse range of stacked and twisted two-dimensional materials

H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments

BACKGROUND: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to the examination of individual positions, the investigation of co-variation of amino acid frequencies offers insights into function and evolution of the protein and residues. RESULTS: We introduce conn(k), a novel parameter for the characterisation of individual residues. For each residue k, conn(k) is the number of most extreme signals of co-evolution. These signals were deduced from a normalised mutual information (MI) value U(k, l) computed for all pairs of residues k, l. We demonstrate that conn(k) is a more robust indicator than an individual MI-value for the prediction of residues most plausibly important for the evolution of a protein. This proposition was inferred by means of statistical methods. It was further confirmed by the analysis of several proteins. A server, which computes conn(k)-values is available at http://www-bioinf.uni-regensburg.de. CONCLUSION: The algorithms H2r, which analyses MSAs and computes conn(k)-values, characterises a specific class of residues. In contrast to strictly conserved ones, these residues possess some flexibility in the composition of side chains. However, their allocation is sensibly balanced with several other positions, as indicated by conn(k)

Socioemotional wealth in family firms: a longitudinal content analysis of corporate disclosures

This is the Accepted Manuscript of the article published in Journal of Family Business Strategy, 2019, 10(2), pp. 119-132, available online: https://doi.org/10.1016/j.jfbs.2018.11.002. Please cite the published version. This Accepted Manuscript is deposited under a CC-BY-NC-ND license.Family business literature has noted the nature and presence of socioemotional wealth (SEW) in family firms. One method of observing SEW is by a five-dimension approach, collectively termed FIBER. While the dimensions are well defined, they have been critiqued, as have the theoretical foundations of SEW. Regardless, given the concept of SEW is about a decade old and the FIBER dimensions less so, it is reasonable to argue more research is needed. One potentially useful research approach is an historical one, which we will here term SEW history – the use of historical research to support (or question) the development of SEW as a concept. We undertake a content analysis of corporate disclosures through the Chairman’s Statement of two Irish family breweries over a period of about two decades. To conduct the analysis, we develop a coding scheme based on the FIBER dimensions and offer some research propositions around these dimensions of SEW being stable (or not) over time. Our findings reveal that the Chairman’s Statement does include FIBER dimensions in both breweries and they do change over time. Subsequent statistical analysis reveals significant differences in the FIBER dimensions between the two breweries and context is revealed as a key issue in the assessment of SEW, something prior research has noted. The study also raises some questions on the nature of some FIBER dimensions, in particular the “I” dimension. This is the Accepted Manuscript of the article published in Journal of Family Business Strategy, 2019, 10(2), pp. 119-132, available online: https://doi.org/10.1016/j.jfbs.2018.11.002. Please cite the published version. This Accepted Manuscript is deposited under a CC-BY-NC-ND license

Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

The inclusive and dijet production cross-sections have been measured for jets containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The measurements use data corresponding to an integrated luminosity of 34 pb^-1. The b-jets are identified using either a lifetime-based method, where secondary decay vertices of b-hadrons in jets are reconstructed using information from the tracking detectors, or a muon-based method where the presence of a muon is used to identify semileptonic decays of b-hadrons inside jets. The inclusive b-jet cross-section is measured as a function of transverse momentum in the range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet cross-section is measured as a function of the dijet invariant mass in the range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets and the angular variable chi in two dijet mass regions. The results are compared with next-to-leading-order QCD predictions. Good agreement is observed between the measured cross-sections and the predictions obtained using POWHEG + Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet cross-section. However, it does not reproduce the measured inclusive cross-section well, particularly for central b-jets with large transverse momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final version published in European Physical Journal

Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutralino lifetime. Limits are presented for different squark and neutralino masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final version to appear in Physics Letters